Insights into the Involvement of Spliceosomal Mutations in Myelodysplastic Disorders from Analysis of SACY-1/DDX41 in Caenorhabditis elegans

Mutations affecting spliceosomal proteins are frequently found in hematological malignancies, including myelodysplastic syndromes and acute myeloid leukemia (AML). DDX41/Abstrakt is a metazoan-specific spliceosomal DEAD-box RNA helicase that is recurrently mutated in inherited myelodysplastic syndro...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Tatsuya, Gearhart, Micah D., Kim, Seongseop, Mekonnen, Gemechu, Spike, Caroline A., Greenstein, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153925/
https://www.ncbi.nlm.nih.gov/pubmed/32060018
http://dx.doi.org/10.1534/genetics.119.302973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153925/
https://www.ncbi.nlm.nih.gov/pubmed/32060018
http://dx.doi.org/10.1534/genetics.119.302973

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