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Effects of Hydroxysafflor Yellow A on the PI3K/AKT Pathway and Apoptosis of Pancreatic β-Cells in Type 2 Diabetes Mellitus Rats

BACKGROUND AND AIM: Type 2 diabetes mellitus (T2DM), a complex metabolic disease, has become a major public health issue around the world. Hydroxysafflor yellow A (HSYA) is the major active chemical ingredient of Carthamus tinctorius L. (safflower), which is widely used in patients with cardiovascul...

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Detalles Bibliográficos
Autores principales: Lee, Maosheng, Li, Huilin, Zhao, Hengxia, Suo, Miao, Liu, Deliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154009/
https://www.ncbi.nlm.nih.gov/pubmed/32308459
http://dx.doi.org/10.2147/DMSO.S246381