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miR-138 Increases Depressive-Like Behaviors by Targeting SIRT1 in Hippocampus

BACKGROUND: Major depressive disorder (MDD) is a serious and common mood disorder with unknown etiology. Emerging evidence has demonstrated the critical roles of SIRT1 and microRNAs (miRNAs) in the progression of MDD. However, the underlying molecular mechanisms remain to be fully understood. METHOD...

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Detalles Bibliográficos
Autores principales: Li, Cuixia, Wang, Feng, Miao, Pei, Yan, Libo, Liu, Silin, Wang, Xian, Jin, Zuolin, Gu, Zexu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154038/
https://www.ncbi.nlm.nih.gov/pubmed/32308399
http://dx.doi.org/10.2147/NDT.S237558