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Loss of Myeloid BMPR1a Alters Differentiation and Reduces Mouse Prostate Cancer Growth

The Bone Morphogenetic Protein (BMP) pathway is a member of the TGFβ signaling family and has complex roles in cancer. BMP signaling is rarely mutated and can be frequently overexpressed in many human cancers. The dichotomous role of BMPs as both tumor promoters and suppressors appears to be largely...

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Detalles Bibliográficos
Autores principales: Ihle, Claire L., Straign, Desiree M., Provera, Meredith D., Novitskiy, Sergey V., Owens, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154049/
https://www.ncbi.nlm.nih.gov/pubmed/32318332
http://dx.doi.org/10.3389/fonc.2020.00357