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Ethionine Suppresses Mitochondria Autophagy and Induces Apoptosis via Activation of Reactive Oxygen Species in Neural Tube Defects

Abnormal development of central nervous system (CNS) caused by neural tube defects (NTDs) is not only remained the major contributor in the prevalence of stillbirths and neonatal deaths, but also represents a significant cause of lifelong physical disability in the surviving infants. Ethionine is a...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Dong, Yanting, Wang, Wenzhuo, Zhao, Taoran, Huang, Tingjuan, Khan, Ajab, Wang, Lei, Liu, Zhizhen, Xie, Jun, Niu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154092/
https://www.ncbi.nlm.nih.gov/pubmed/32318018
http://dx.doi.org/10.3389/fneur.2020.00242