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Effect for Human Genomic Variation During the BMP4-Induced Conversion From Pluripotent Stem Cells to Trophoblast

The role of genomic variation in differentiation is currently not well understood. Here, the genomic variations were determined with the whole-genome sequencing for three pairs of pluripotent stem cell lines and their corresponding BMP4-induced trophoblast cell lines. We identified ∼3,500 single nuc...

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Detalles Bibliográficos
Autores principales: Li, Hai-tao, Liu, Yajun, Liu, Hongde, Sun, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154154/
https://www.ncbi.nlm.nih.gov/pubmed/32318089
http://dx.doi.org/10.3389/fgene.2020.00230