A T Cell Receptor Sequencing-Based Assay Identifies Cross-Reactive Recall CD8(+) T Cell Clonotypes Against Autologous HIV-1 Epitope Variants

HIV-1 positive elite controllers or suppressors control viral replication without antiretroviral therapy, likely via CTL-mediated elimination of infected cells, and therefore represent a model of an HIV-1 functional cure. Efforts to cure HIV-1 accordingly rely on the existence or generation of antig...

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Detalles Bibliográficos
Autores principales: Chan, Hok Yee, Zhang, Jiajia, Garliss, Caroline C., Kwaa, Abena K., Blankson, Joel N., Smith, Kellie N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154155/
https://www.ncbi.nlm.nih.gov/pubmed/32318072
http://dx.doi.org/10.3389/fimmu.2020.00591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154155/
https://www.ncbi.nlm.nih.gov/pubmed/32318072
http://dx.doi.org/10.3389/fimmu.2020.00591

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