Cargando…

A T Cell Receptor Sequencing-Based Assay Identifies Cross-Reactive Recall CD8(+) T Cell Clonotypes Against Autologous HIV-1 Epitope Variants

HIV-1 positive elite controllers or suppressors control viral replication without antiretroviral therapy, likely via CTL-mediated elimination of infected cells, and therefore represent a model of an HIV-1 functional cure. Efforts to cure HIV-1 accordingly rely on the existence or generation of antig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chan, Hok Yee, Zhang, Jiajia, Garliss, Caroline C., Kwaa, Abena K., Blankson, Joel N., Smith, Kellie N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154155/ https://www.ncbi.nlm.nih.gov/pubmed/32318072 http://dx.doi.org/10.3389/fimmu.2020.00591

Ejemplares similares

A Comparison of Different Immune Activation Strategies to Reverse HIV-1 Latency
por: Garliss, Caroline C, et al.
Publicado: (2020)

CD4(+) T cells from COVID-19 mRNA vaccine recipients recognize a conserved epitope present in diverse coronaviruses
por: Woldemeskel, Bezawit A., et al.
Publicado: (2022)

Viral reservoirs in elite controllers of HIV-1 infection: Implications for HIV cure strategies
por: Woldemeskel, Bezawit A., et al.
Publicado: (2020)

The effect of Ingenol-B on the suppressive capacity of elite suppressor HIV-specific CD8+ T cells
por: Kwaa, Abena K., et al.
Publicado: (2017)

Combined Effects of HLA-B*57/5801 Elite Suppressor CD8+ T Cells and NK Cells on HIV-1 Replication
por: May, Megan E., et al.
Publicado: (2020)

CD8 Effector T Cells Function Synergistically With Broadly Neutralizing Antibodies to Enhance Suppression of HIV Infection
por: Veenhuis, Rebecca T., et al.
Publicado: (2021)

A CD3/CD28 microbead-based HIV-1 viral outgrowth assay
por: Kuzmichev, Yury V, et al.
Publicado: (2017)

SARS-CoV-2 vaccination diversifies the CD4+ spike-reactive T cell repertoire in patients with prior SARS-CoV-2 infection
por: Dykema, Arbor G., et al.
Publicado: (2022)

T-cell clonotypes in cancer
por: thor Straten, Per, et al.
Publicado: (2004)

A clonotype nomenclature for T cell receptors
por: Yassai, Maryam B., et al.
Publicado: (2009)

Programmed death-1 expression on HIV-1-specific CD8(+) T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load
por: Kløverpris, Henrik N., et al.
Publicado: (2014)

Proviral location affects cognate peptide–induced virus production and immune recognition of HIV-1–infected T cell clones
por: Dragoni, Filippo, et al.
Publicado: (2023)

Multiple modes of antigen exposure induce clonotypically diverse epitope-specific CD8(+) T cells across multiple tissues in nonhuman primates
por: Simpson, Jennifer, et al.
Publicado: (2022)

SURROGATE SELECTION OVERSAMPLES EXPANDED T CELL CLONOTYPES
por: Yu, Peng, et al.
Publicado: (2023)

Cross-reactive microbial peptides can modulate HIV-specific CD8(+) T cell responses
por: Pohlmeyer, Christopher W., et al.
Publicado: (2018)

High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires
por: Soto, Cinque, et al.
Publicado: (2020)

Localization of T cell clonotypes using the Visium spatial transcriptomics platform
por: Hudson, William H., et al.
Publicado: (2022)

Distinct vascular lesions in giant cell arteritis share identical T cell clonotypes
Publicado: (1994)

Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response
por: Merkenschlager, Julia, et al.
Publicado: (2016)

Clinical and basic implications of dynamic T cell receptor clonotyping in hematopoietic cell transplantation
por: Pagliuca, Simona, et al.
Publicado: (2021)

Clonotype pattern in T-cell lymphomas map the cell of origin to immature lymphoid precursors
por: Iyer, Aishwarya, et al.
Publicado: (2022)

Distinct phenotypic states and spatial distribution of CD8(+) T cell clonotypes in human brain metastases
por: Sudmeier, Lisa J., et al.
Publicado: (2022)

Peptide–MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations
por: Rius, Cristina, et al.
Publicado: (2018)

Stochastic descriptors to study the fate and potential of naive T cell clonotypes in the periphery
por: Artalejo, J. R., et al.
Publicado: (2016)

Anticlonotypic monoclonal antibodies induce proliferation of clonotype- positive T cells in peripheral blood human T lymphocytes. Evidence for a phenotypic (T4/T8) heterogeneity of the clonotype-positive proliferating cells
Publicado: (1985)

Clonotypically similar hybrid αβ T cell receptors can exhibit markedly different surface expression, antigen specificity and cross‐reactivity
por: Motozono, C., et al.
Publicado: (2015)

Public clonotype usage identifies protective Gag-specific CD8(+) T cell responses in SIV infection
por: Price, David A., et al.
Publicado: (2009)

The CMV-Specific CD8(+) T Cell Response Is Dominated by Supra-Public Clonotypes with High Generation Probabilities
por: Schober, Kilian, et al.
Publicado: (2020)

Urinary T cells are detected in patients with immune checkpoint inhibitor-associated immune nephritis that are clonotypically identical to kidney T cell infiltrates
por: Singh, Shailbala, et al.
Publicado: (2022)

The mouse viral outgrowth assay: avatars for the detection of HIV-1 reservoirs
por: Metcalf Pate, Kelly A., et al.
Publicado: (2017)

Rapid TCR:Epitope Ranker (RAPTER): a primary human T cell reactivity screening assay pairing epitope and TCR at single cell resolution
por: Deering, Raquel P., et al.
Publicado: (2023)

Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients
por: Lu, Xiuyuan, et al.
Publicado: (2021)

Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures
por: Teng, Yvonne H. F., et al.
Publicado: (2021)

Baseline VDJ clonotype detection using a targeted sequencing NGS assay: allowing for subsequent MRD assessment
por: Hultcrantz, Malin, et al.
Publicado: (2020)

Developmentally regulated expression of CD3 components independent of clonotypic T cell antigen receptor complexes on immature thymocytes
Publicado: (1994)

Persistence of EBV Antigen-Specific CD8 T Cell Clonotypes during Homeostatic Immune Reconstitution in Cancer Patients
por: Iancu, Emanuela M., et al.
Publicado: (2013)

Public Clonotypes and Convergent Recombination Characterize the Naïve CD8(+) T-Cell Receptor Repertoire of Extremely Preterm Neonates
por: Carey, Alison J., et al.
Publicado: (2017)

Advances on Cellular Clonotypic Immunity in Amyotrophic Lateral Sclerosis
por: Schirò, Giuseppe, et al.
Publicado: (2022)

Does B Cell Follicle Exclusion of CD8+ T Cells Make Lymph Nodes Sanctuaries of HIV Replication?
por: Beck, Sarah E., et al.
Publicado: (2019)

Low neutralisation of the omicron BA.2 sublineage in boosted individuals who had breakthrough infections
por: Karaba, Andrew H, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_njthd8lmk599epfuvfo0ff019g