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Dopaminergic Progenitors Derived From Epiblast Stem Cells Function Similarly to Primary VM-Derived Progenitors When Transplanted Into a Parkinson’s Disease Model

Neural transplantation in neurodegenerative diseases such as Parkinson’s disease (PD) offers to replace cells lost during the progression of the disease process. Primary fetal ventral mesencephalon (VM), the origin of bona fide midbrain dopaminergic (DAergic) precursors, is currently the gold standa...

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Detalles Bibliográficos
Autores principales: Precious, Sophie V., Smith, Gaynor A., Heuer, Andreas, Jaeger, Ines, Lane, Emma L., Dunnett, Stephen B., Li, Meng, Kelly, Claire M., Rosser, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154167/
https://www.ncbi.nlm.nih.gov/pubmed/32317925
http://dx.doi.org/10.3389/fnins.2020.00312