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Dopaminergic Progenitors Derived From Epiblast Stem Cells Function Similarly to Primary VM-Derived Progenitors When Transplanted Into a Parkinson’s Disease Model
Neural transplantation in neurodegenerative diseases such as Parkinson’s disease (PD) offers to replace cells lost during the progression of the disease process. Primary fetal ventral mesencephalon (VM), the origin of bona fide midbrain dopaminergic (DAergic) precursors, is currently the gold standa...
Autores principales: | Precious, Sophie V., Smith, Gaynor A., Heuer, Andreas, Jaeger, Ines, Lane, Emma L., Dunnett, Stephen B., Li, Meng, Kelly, Claire M., Rosser, Anne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154167/ https://www.ncbi.nlm.nih.gov/pubmed/32317925 http://dx.doi.org/10.3389/fnins.2020.00312 |
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