Mutations within the Activation Loop Domain of FLT3 in Two Pediatric Patients with Refractory Infant Acute Myeloid Leukemia

Approximately 24% of all pediatric acute myeloid leukemia (AML) cases have mutations in the FMS-like tyrosine kinase 3 (FLT3) receptor gene. FLT3-TKD point mutations are rare in pediatrics and often occur in younger patients and in combination with 11q23 abnormalities. There is a paucity of data rel...

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Detalles Bibliográficos
Autores principales: Muhlbauer, Nicole, MacDonell-Yilmaz, Rebecca E., Borsuk, Robyn, Welch, Jennifer G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154245/
https://www.ncbi.nlm.nih.gov/pubmed/32308588
http://dx.doi.org/10.1159/000506194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154245/
https://www.ncbi.nlm.nih.gov/pubmed/32308588
http://dx.doi.org/10.1159/000506194

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