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Clinical pharmacokinetics and drug exposure-toxicity correlation study of docetaxel based chemotherapy in Chinese head and neck cancer patients

BACKGROUND: Area under time-concentration curve (AUC) of docetaxel is related with its toxicity and efficacy. The aim of this study is to investigate the target range of docetaxel AUC in Chinese head and neck cancer (HNC) patients. METHODS: Eligible HNC patients were enrolled and received at least 2...

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Detalles Bibliográficos
Autores principales: Ma, Yuxiang, Lin, Qingguang, Yang, Yunpeng, Liang, Weiting, Salamone, S. J., Li, Yunying, Lin, Yuehao, Zhao, Hongyun, Zhao, Yuanyuan, Fang, Wenfeng, Huang, Yan, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154422/
https://www.ncbi.nlm.nih.gov/pubmed/32309383
http://dx.doi.org/10.21037/atm.2020.01.76