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Palmitic acid stimulates NLRP3 inflammasome activation through TLR4-NF-κB signal pathway in hepatic stellate cells

BACKGROUND: The NLRP3 inflammasome activation plays an important role in the development of NASH and fibrogenesis. However, the mechanisms involved in NLRP3 activation in hepatic stellate cells (HSCs) have been unclear. The aim of this study was to investigate the mechanism of NLRP3 activation in HS...

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Detalles Bibliográficos
Autores principales: Dong, Zhixia, Zhuang, Qian, Ning, Min, Wu, Shan, Lu, Lungen, Wan, Xinjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154441/
https://www.ncbi.nlm.nih.gov/pubmed/32309315
http://dx.doi.org/10.21037/atm.2020.02.21