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Blockade of BDNF signalling attenuates chronic visceral hypersensitivity in an IBS‐like rat model

BACKGROUND: Irritable bowel syndrome (IBS) is a common functional disease characterized by chronic abdominal pain and changes in bowel movements. Effective therapy for visceral hypersensitivity in IBS patients remains challenging. This study investigated the roles of brain‐derived neurotrophic facto...

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Detalles Bibliográficos
Autores principales: Fan, Fei, Tang, Ying, Dai, Hengfen, Cao, Yang, Sun, Pei, Chen, Yu, Chen, Aiqin, Lin, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154558/
https://www.ncbi.nlm.nih.gov/pubmed/31976585
http://dx.doi.org/10.1002/ejp.1534