Enantioselective Synthesis of 1,12‐Disubstituted [4]Helicenes

A highly enantioselective synthesis of 1,12‐disubstituted [4]carbohelicenes is reported. The key step for the developed synthetic route is a Au‐catalyzed intramolecular alkyne hydroarylation, which is achieved with good to excellent regio‐ and enantioselectivity by employing TADDOL‐derived (TADDOL=α...

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Detalles Bibliográficos
Autores principales: Hartung, Thierry, Machleid, Rafael, Simon, Martin, Golz, Christopher, Alcarazo, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154633/
https://www.ncbi.nlm.nih.gov/pubmed/31961992
http://dx.doi.org/10.1002/anie.201915870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154633/
https://www.ncbi.nlm.nih.gov/pubmed/31961992
http://dx.doi.org/10.1002/anie.201915870

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