Ambident Nucleophilic Substitution: Understanding Non‐HSAB Behavior through Activation Strain and Conceptual DFT Analyses

The ability to understand and predict ambident reactivity is key to the rational design of organic syntheses. An approach to understand trends in ambident reactivity is the hard and soft acids and bases (HSAB) principle. The recent controversy over the general validity of this principle prompted us...

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Detalles Bibliográficos
Autores principales: Bettens, Tom, Alonso, Mercedes, De Proft, Frank, Hamlin, Trevor A., Bickelhaupt, F. Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154642/
https://www.ncbi.nlm.nih.gov/pubmed/31957943
http://dx.doi.org/10.1002/chem.202000272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154642/
https://www.ncbi.nlm.nih.gov/pubmed/31957943
http://dx.doi.org/10.1002/chem.202000272

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