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Association Between Toll‐Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Genetic Variants and Clinical Progression of Huntington's Disease

BACKGROUND: Although Huntington's disease (HD) is caused by a single dominant gene, it is clear that there are genetic modifiers that may influence the age of onset and disease progression. OBJECTIVES: We sought to investigate whether new inflammation‐related genetic variants may contribute to...

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Detalles Bibliográficos
Autores principales: Vuono, Romina, Kouli, Antonina, Legault, Emilie M., Chagnon, Lauriane, Allinson, Kieren S., La Spada, Alberto, Biunno, Ida, Barker, Roger A., Drouin‐Ouellet, Janelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154663/
https://www.ncbi.nlm.nih.gov/pubmed/31724242
http://dx.doi.org/10.1002/mds.27911