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Association Between Toll‐Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Genetic Variants and Clinical Progression of Huntington's Disease
BACKGROUND: Although Huntington's disease (HD) is caused by a single dominant gene, it is clear that there are genetic modifiers that may influence the age of onset and disease progression. OBJECTIVES: We sought to investigate whether new inflammation‐related genetic variants may contribute to...
Autores principales: | Vuono, Romina, Kouli, Antonina, Legault, Emilie M., Chagnon, Lauriane, Allinson, Kieren S., La Spada, Alberto, Biunno, Ida, Barker, Roger A., Drouin‐Ouellet, Janelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154663/ https://www.ncbi.nlm.nih.gov/pubmed/31724242 http://dx.doi.org/10.1002/mds.27911 |
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