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Components of the endocytic and recycling trafficking pathways interfere with the integrity of the Legionella‐containing vacuole
Legionella pneumophila requires the Dot/Icm translocation system to replicate in a vacuolar compartment within host cells. Strains lacking the translocated substrate SdhA form a permeable vacuole during residence in the host cell, exposing bacteria to the host cytoplasm. In primary macrophages, muta...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154685/ https://www.ncbi.nlm.nih.gov/pubmed/32096265 http://dx.doi.org/10.1111/cmi.13151 |