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Poor old pores—The challenge of making and maintaining nuclear pore complexes in aging

The nuclear pore complex (NPC) is the sole gateway to the nuclear interior, and its function is essential to all eukaryotic life. Controlling the functionality of NPCs is a tremendous challenge for cells. Firstly, NPCs are large structures, and their complex assembly does occasionally go awry. Secon...

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Detalles Bibliográficos
Autores principales: Rempel, Irina L., Steen, Anton, Veenhoff, Liesbeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154712/
https://www.ncbi.nlm.nih.gov/pubmed/31912972
http://dx.doi.org/10.1111/febs.15205