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Changes in thalamic dopamine innervation in a progressive Parkinson's disease model in monkeys

BACKGROUND: Dopamine loss beyond the mesostriatal system might be relevant in pathogenic mechanisms and some clinical manifestations in PD. The primate thalamus is densely and heterogeneously innervated with dopaminergic axons, most of which express the dopamine transporter, as does the nigrostriata...

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Detalles Bibliográficos
Autores principales: Monje, Mariana H.G., Blesa, Javier, García‐Cabezas, Miguel Ángel, Obeso, José A., Cavada, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154739/
https://www.ncbi.nlm.nih.gov/pubmed/31800134
http://dx.doi.org/10.1002/mds.27921