Synthesis of gem‐Difluoro Olefins through C−H Functionalization and β‐fluoride Elimination Reactions

A palladium catalyzed C−H functionalization and consecutive β‐fluoride elimination reaction between indole heterocycles and fluorinated diazoalkanes is reported. This approach provides for the first time a facile method for the rapid synthesis of gem‐difluoro olefins using fluorinated diazoalkanes u...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Zhen, Möller, Mieke, Koenigs, Rene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155031/
https://www.ncbi.nlm.nih.gov/pubmed/31885145
http://dx.doi.org/10.1002/anie.201915500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155031/
https://www.ncbi.nlm.nih.gov/pubmed/31885145
http://dx.doi.org/10.1002/anie.201915500

Ejemplares similares