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Synthesis of gem‐Difluoro Olefins through C−H Functionalization and β‐fluoride Elimination Reactions
A palladium catalyzed C−H functionalization and consecutive β‐fluoride elimination reaction between indole heterocycles and fluorinated diazoalkanes is reported. This approach provides for the first time a facile method for the rapid synthesis of gem‐difluoro olefins using fluorinated diazoalkanes u...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155031/ https://www.ncbi.nlm.nih.gov/pubmed/31885145 http://dx.doi.org/10.1002/anie.201915500 |