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Cerebral oxygen metabolism in adults with sickle cell disease

In sickle cell disease (SCD), oxygen delivery is impaired due to anemia, especially during times of increased metabolic demand, and cerebral blood flow (CBF) must increase to meet changing physiologic needs. But hyperemia limits cerebrovascular reserve (CVR) and ischemic risk prevails despite elevat...

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Detalles Bibliográficos
Autores principales: Václavů, Lena, Petr, Jan, Petersen, Esben Thade, Mutsaerts, Henri J.M.M., Majoie, Charles B.L., Wood, John C., VanBavel, Ed, Nederveen, Aart J., Biemond, Bart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155077/
https://www.ncbi.nlm.nih.gov/pubmed/31919876
http://dx.doi.org/10.1002/ajh.25727