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Human endothelial cells size‐select their secretory granules for exocytosis to modulate their functional output

BACKGROUND: The secretory granules of endothelial cells, Weibel‐Palade bodies, are released in response to numerous extracellular signals. Their cargo is critical to many vascular functions including hemostasis and inflammation. This presents a fundamental problem: how can these cells initiate tailo...

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Detalles Bibliográficos
Autores principales: McCormack, Jessica J., Harrison‐Lavoie, Kimberly J., Cutler, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155122/
https://www.ncbi.nlm.nih.gov/pubmed/31519030
http://dx.doi.org/10.1111/jth.14634