A simple, versatile and robust centrifugation‐based filtration protocol for the isolation and quantification of α‐synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α‐synuclein research

Increasing evidence suggests that the process of alpha‐synuclein (α‐syn) aggregation from monomers into amyloid fibrils and Lewy bodies, via oligomeric intermediates plays an essential role in the pathogenesis of different synucleinopathies, including Parkinson's disease (PD), multiple system a...

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Detalles Bibliográficos
Autores principales: Kumar, Senthil T., Donzelli, Sonia, Chiki, Anass, Syed, Muhammed Muazzam Kamil, Lashuel, Hilal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155127/
https://www.ncbi.nlm.nih.gov/pubmed/31925956
http://dx.doi.org/10.1111/jnc.14955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155127/
https://www.ncbi.nlm.nih.gov/pubmed/31925956
http://dx.doi.org/10.1111/jnc.14955

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