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Medroxyprogesterone Acetate Impairs Amyloid Beta Degradation in a Matrix Metalloproteinase-9 Dependent Manner

Despite the extensive use of hormonal methods as either contraception or menopausal hormone therapy (HT), there is very little known about the potential effects of these compounds on the cellular processes of the brain. Medroxyprogesterone Acetate (MPA) is a progestogen used globally in the hormonal...

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Detalles Bibliográficos
Autores principales: Porter, Keyana N., Sarkar, Saumyendra N., Dakhlallah, Duaa A., Vannoy, Mya E., Quintana, Dominic D., Simpkins, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155169/
https://www.ncbi.nlm.nih.gov/pubmed/32317959
http://dx.doi.org/10.3389/fnagi.2020.00092