Inference of single-cell phylogenies from lineage tracing data using Cassiopeia

The pairing of CRISPR/Cas9-based gene editing with massively parallel single-cell readouts now enables large-scale lineage tracing. However, the rapid growth in complexity of data from these assays has outpaced our ability to accurately infer phylogenetic relationships. First, we introduce Cassiopei...

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Detalles Bibliográficos
Autores principales: Jones, Matthew G, Khodaverdian, Alex, Quinn, Jeffrey J, Chan, Michelle M, Hussmann, Jeffrey A, Wang, Robert, Xu, Chenling, Weissman, Jonathan S, Yosef, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155257/
https://www.ncbi.nlm.nih.gov/pubmed/32290857
http://dx.doi.org/10.1186/s13059-020-02000-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155257/
https://www.ncbi.nlm.nih.gov/pubmed/32290857
http://dx.doi.org/10.1186/s13059-020-02000-8

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