Cargando…

Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism

BACKGROUND: Orotic acid (OA) has been intensively utilized to induce fatty liver in rats. Although the capacity of OA to cause steatosis is species-specific, previous in vitro studies indicate that humans could also be susceptible to OA-induced fatty liver. The aim of the present study was to re-elu...

Descripción completa

Detalles Bibliográficos
Autores principales: Matilainen, Johanna, Mustonen, Anne-Mari, Rilla, Kirsi, Käkelä, Reijo, Sihvo, Sanna P., Nieminen, Petteri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155272/
https://www.ncbi.nlm.nih.gov/pubmed/32284043
http://dx.doi.org/10.1186/s12944-020-01243-5