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Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism
BACKGROUND: Orotic acid (OA) has been intensively utilized to induce fatty liver in rats. Although the capacity of OA to cause steatosis is species-specific, previous in vitro studies indicate that humans could also be susceptible to OA-induced fatty liver. The aim of the present study was to re-elu...
Autores principales: | Matilainen, Johanna, Mustonen, Anne-Mari, Rilla, Kirsi, Käkelä, Reijo, Sihvo, Sanna P., Nieminen, Petteri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155272/ https://www.ncbi.nlm.nih.gov/pubmed/32284043 http://dx.doi.org/10.1186/s12944-020-01243-5 |
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