Curcumin Regulates the r(CGG)(exp) RNA Hairpin Structure and Ameliorate Defects in Fragile X-Associated Tremor Ataxia Syndrome

Fragile X-associated tremor ataxia syndrome is an untreatable neurological and neuromuscular disorder caused by unstable expansion of 55–200 CGG nucleotide repeats in 5′ UTR of Fragile X intellectual disability 1 (FMR1) gene. The expansion of CGG repeats in the FMR1 mRNA elicits neuronal cell toxici...

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Detalles Bibliográficos
Autores principales: Verma, Arun Kumar, Khan, Eshan, Mishra, Subodh Kumar, Mishra, Amit, Charlet-Berguerand, Nicolas, Kumar, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155420/
https://www.ncbi.nlm.nih.gov/pubmed/32317919
http://dx.doi.org/10.3389/fnins.2020.00295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155420/
https://www.ncbi.nlm.nih.gov/pubmed/32317919
http://dx.doi.org/10.3389/fnins.2020.00295

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