Resveratrol Sensitizes Colorectal Cancer Cells to Cetuximab by Connexin 43 Upregulation-Induced Akt Inhibition

Cetuximab is a monoclonal antibody that acts as an anti-epidermal growth factor receptor (EGFR) agent. Cetuximab inhibits the phosphorylation and activation of EGFR and blocks downstream signal pathways of EGF/EGFR, including Ras-Raf-MAPK and PI3K-Akt pathways. Akt activation is an important factor...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yijia, Wang, Wenhong, Wu, Xiaojing, Li, Chunjun, Huang, Yaping, Zhou, Huiyan, Cui, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155766/
https://www.ncbi.nlm.nih.gov/pubmed/32318334
http://dx.doi.org/10.3389/fonc.2020.00383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155766/
https://www.ncbi.nlm.nih.gov/pubmed/32318334
http://dx.doi.org/10.3389/fonc.2020.00383

Ejemplares similares