Establishing a nonlethal and efficient mouse model of male gonadotoxicity by intraperitoneal busulfan injection

An ideal animal model of azoospermia would be a powerful tool for the evaluation of spermatogonial stem cell (SSC) transplantation. Busulfan has been commonly used to develop such a model, but 30%–87% of mice die when administered an intraperitoneal injection of 40 mg kg(−1). In the present study, h...

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Detalles Bibliográficos
Autores principales: Xie, Yun, Deng, Cun-Can, Ouyang, Bin, Lv, Lin-Yan, Yao, Jia-Hui, Zhang, Chi, Chen, Hai-Cheng, Liang, Xiao-Yan, Sun, Xiang-Zhou, Deng, Chun-Hua, Liu, Gui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155790/
https://www.ncbi.nlm.nih.gov/pubmed/31187778
http://dx.doi.org/10.4103/aja.aja_41_19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155790/
https://www.ncbi.nlm.nih.gov/pubmed/31187778
http://dx.doi.org/10.4103/aja.aja_41_19

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