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Establishing a nonlethal and efficient mouse model of male gonadotoxicity by intraperitoneal busulfan injection
An ideal animal model of azoospermia would be a powerful tool for the evaluation of spermatogonial stem cell (SSC) transplantation. Busulfan has been commonly used to develop such a model, but 30%–87% of mice die when administered an intraperitoneal injection of 40 mg kg(−1). In the present study, h...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer - Medknow
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155790/ https://www.ncbi.nlm.nih.gov/pubmed/31187778 http://dx.doi.org/10.4103/aja.aja_41_19 |