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A Brain Signaling Framework for Stress-Induced Depression and Ketamine Treatment Elucidated by Phosphoproteomics

Depression is a common affective disorder characterized by significant and persistent low mood. Ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, is reported to have a rapid and durable antidepressant effect, but the mechanisms are unclear. Protein phosphorylation is a post-translationa...

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Detalles Bibliográficos
Autores principales: Xiao, Yan, Luo, Huoqing, Yang, Wen Z., Zeng, Yeting, Shen, Yinbo, Ni, Xinyan, Shi, Zhaomei, Zhong, Jun, Liang, Ziqi, Fu, Xiaoyu, Tu, Hongqing, Sun, Wenzhi, Shen, Wei L., Hu, Ji, Yang, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156020/
https://www.ncbi.nlm.nih.gov/pubmed/32317933
http://dx.doi.org/10.3389/fncel.2020.00048