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Shared Genetic Risk Factors Across Carbamazepine‐Induced Hypersensitivity Reactions

Carbamazepine (CBZ) causes life‐threating T‐cell‐mediated hypersensitivity reactions, including serious cutaneous adverse reactions (SCARs) and drug‐induced liver injury (CBZ‐DILI). In order to evaluate shared or phenotype‐specific genetic predisposing factors for CBZ hypersensitivity reactions, we...

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Detalles Bibliográficos
Autores principales: Nicoletti, Paola, Barrett, Sarah, McEvoy, Laurence, Daly, Ann K., Aithal, Guruprasad, Lucena, M. Isabel, Andrade, Raul J., Wadelius, Mia, Hallberg, Pär, Stephens, Camilla, Bjornsson, Einar S., Friedmann, Peter, Kainu, Kati, Laitinen, Tarja, Marson, Anthony, Molokhia, Mariam, Phillips, Elizabeth, Pichler, Werner, Romano, Antonino, Shear, Neil, Sills, Graeme, Tanno, Luciana K., Swale, Ashley, Floratos, Aris, Shen, Yufeng, Nelson, Matthew R., Watkins, Paul B., Daly, Mark J., Morris, Andrew P., Alfirevic, Ana, Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156285/
https://www.ncbi.nlm.nih.gov/pubmed/31066027
http://dx.doi.org/10.1002/cpt.1493