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Increased macrophages and changed brain endothelial cell gene expression in the frontal cortex of people with schizophrenia displaying inflammation

Elevated pro-inflammatory cytokines exist in both blood and brain of people with schizophrenia but how this affects molecular indices of the blood–brain barrier (BBB) is unclear. Eight mRNAs relating to BBB function, a microglia and three immune cell markers were measured by qPCR in the prefrontal c...

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Detalles Bibliográficos
Autores principales: Cai, Helen Q., Catts, Vibeke S., Webster, Maree J., Galletly, Cherrie, Liu, Dennis, O’Donnell, Maryanne, Weickert, Thomas W, Weickert, Cynthia Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156343/
https://www.ncbi.nlm.nih.gov/pubmed/30214039
http://dx.doi.org/10.1038/s41380-018-0235-x