Cargando…
Increased macrophages and changed brain endothelial cell gene expression in the frontal cortex of people with schizophrenia displaying inflammation
Elevated pro-inflammatory cytokines exist in both blood and brain of people with schizophrenia but how this affects molecular indices of the blood–brain barrier (BBB) is unclear. Eight mRNAs relating to BBB function, a microglia and three immune cell markers were measured by qPCR in the prefrontal c...
Autores principales: | Cai, Helen Q., Catts, Vibeke S., Webster, Maree J., Galletly, Cherrie, Liu, Dennis, O’Donnell, Maryanne, Weickert, Thomas W, Weickert, Cynthia Shannon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156343/ https://www.ncbi.nlm.nih.gov/pubmed/30214039 http://dx.doi.org/10.1038/s41380-018-0235-x |
Ejemplares similares
-
Using blood cytokine measures to define high inflammatory biotype of schizophrenia and schizoaffective disorder
por: Boerrigter, Danny, et al.
Publicado: (2017) -
O1.5. ICAM-1 IS INCREASED IN BRAIN AND PERIPHERAL LEVELS OF SOLUBLE ICAM-1 IS RELATED TO COGNITIVE DEFICITS IN SCHIZOPHRENIA
por: Weickert, Thomas, et al.
Publicado: (2018) -
Relationship between somatostatin and death receptor expression in the orbital frontal cortex in schizophrenia: a postmortem brain mRNA study
por: Joshi, Dipesh, et al.
Publicado: (2015) -
Peripheral NF-κB dysregulation in people with schizophrenia drives inflammation: putative anti-inflammatory functions of NF-κB kinases
por: Murphy, Caitlin E., et al.
Publicado: (2022) -
Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia
por: Kindler, Jochen, et al.
Publicado: (2019)