The dynactin subunit DCTN1 controls osteoclastogenesis via the Cdc42/PAK2 pathway

Osteoclasts (OCs), cells specialized for bone resorption, are generated from monocyte/macrophage precursors by a differentiation process governed by RANKL. Here, we show that DCTN1, a key component of the dynactin complex, plays important roles in OC differentiation. The expression of DCTN1 was upre...

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Detalles Bibliográficos
Autores principales: Lee, Yong Deok, Kim, Bongjun, Jung, Suhan, Kim, Haemin, Kim, Min Kyung, Kwon, Jun-Oh, Song, Min-Kyoung, Lee, Zang Hee, Kim, Hong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156411/
https://www.ncbi.nlm.nih.gov/pubmed/32210358
http://dx.doi.org/10.1038/s12276-020-0406-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156411/
https://www.ncbi.nlm.nih.gov/pubmed/32210358
http://dx.doi.org/10.1038/s12276-020-0406-0

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