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Capturing the primordial Kras mutation initiating urethane carcinogenesis
The environmental carcinogen urethane exhibits a profound specificity for pulmonary tumors driven by an oncogenic Q(61)L/R mutation in the gene Kras. Similarly, the frequency, isoform, position, and substitution of oncogenic RAS mutations are often unique to human cancers. To elucidate the principle...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156420/ https://www.ncbi.nlm.nih.gov/pubmed/32286309 http://dx.doi.org/10.1038/s41467-020-15660-8 |