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Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones

A synthetic biology method based on heterologous biosynthesis coupled with genome mining is a promising approach for increasing the opportunities to rationally access natural product with novel structures and biological activities through total biosynthesis and combinatorial biosynthesis. Here, we d...

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Detalles Bibliográficos
Autores principales: Tsukada, Kento, Shinki, Shono, Kaneko, Akiho, Murakami, Kazuma, Irie, Kazuhiro, Murai, Masatoshi, Miyoshi, Hideto, Dan, Shingo, Kawaji, Kumi, Hayashi, Hironori, Kodama, Eiichi N., Hori, Aki, Salim, Emil, Kuraishi, Takayuki, Hirata, Naoya, Kanda, Yasunari, Asai, Teigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156458/
https://www.ncbi.nlm.nih.gov/pubmed/32286350
http://dx.doi.org/10.1038/s41467-020-15664-4