The Ap-2α/Elk-1 axis regulates Sirpα-dependent tumor phagocytosis by tumor-associated macrophages in colorectal cancer

The inhibitory receptor signal regulatory protein-α (Sirpα) is a myeloid-specific immune checkpoint that engages the “don’t eat me” signal CD47, which is expressed on tumor and normal tissue cells. However, the profile and regulatory mechanism of Sirpα expression in tumor-associated macrophages (TAM...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojiao, Luo, Xi, Chen, Chuan, Tang, Ye, Li, Lian, Mo, Banghui, Liang, Houjie, Yu, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156469/
https://www.ncbi.nlm.nih.gov/pubmed/32296015
http://dx.doi.org/10.1038/s41392-020-0124-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156469/
https://www.ncbi.nlm.nih.gov/pubmed/32296015
http://dx.doi.org/10.1038/s41392-020-0124-z

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