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Integrating DNA methylation measures to improve clinical risk assessment: are we there yet? The case of BRCA1 methylation marks to improve clinical risk assessment of breast cancer

Current risk prediction models estimate the probability of developing breast cancer over a defined period based on information such as family history, non-genetic breast cancer risk factors, genetic information from high and moderate risk breast cancer susceptibility genes and, over the past several...

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Detalles Bibliográficos
Autores principales: Wong, Ee Ming, Southey, Melissa C., Terry, Mary Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156506/
https://www.ncbi.nlm.nih.gov/pubmed/32066913
http://dx.doi.org/10.1038/s41416-019-0720-2