MOB2 suppresses GBM cell migration and invasion via regulation of FAK/Akt and cAMP/PKA signaling

Mps one binder 2 (MOB2) regulates the NDR kinase family, however, whether and how it is implicated in cancer remain unknown. Here we show that MOB2 functions as a tumor suppressor in glioblastoma (GBM). Analysis of MOB2 expression in glioma patient specimens and bioinformatic analyses of public data...

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Detalles Bibliográficos
Autores principales: Jiang, Ke, Yao, Gang, Hu, Lulu, Yan, Yumei, Liu, Jia, Shi, Ji, Chang, Youwei, Zhang, Ye, Liang, Dapeng, Shen, Dachuan, Zhang, Guirong, Meng, Songshu, Piao, Haozhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156523/
https://www.ncbi.nlm.nih.gov/pubmed/32286266
http://dx.doi.org/10.1038/s41419-020-2381-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156523/
https://www.ncbi.nlm.nih.gov/pubmed/32286266
http://dx.doi.org/10.1038/s41419-020-2381-8

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