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Functionalized Enzyme-Responsive Biomaterials to Model Tissue Stiffening in vitro

The mechanical properties of the cellular microenvironment play a crucial role in modulating cell function, and many pathophysiological processes are accompanied by variations in extracellular matrix (ECM) stiffness. Lysyl oxidase (LOx) is one of the enzymes involved in several ECM-stiffening proces...

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Detalles Bibliográficos
Autores principales: Tirella, Annalisa, Mattei, Giorgio, La Marca, Margherita, Ahluwalia, Arti, Tirelli, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156543/
https://www.ncbi.nlm.nih.gov/pubmed/32322576
http://dx.doi.org/10.3389/fbioe.2020.00208