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Functionalized Enzyme-Responsive Biomaterials to Model Tissue Stiffening in vitro
The mechanical properties of the cellular microenvironment play a crucial role in modulating cell function, and many pathophysiological processes are accompanied by variations in extracellular matrix (ECM) stiffness. Lysyl oxidase (LOx) is one of the enzymes involved in several ECM-stiffening proces...
Autores principales: | Tirella, Annalisa, Mattei, Giorgio, La Marca, Margherita, Ahluwalia, Arti, Tirelli, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156543/ https://www.ncbi.nlm.nih.gov/pubmed/32322576 http://dx.doi.org/10.3389/fbioe.2020.00208 |
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