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Exosome-Derived miR-486-5p Regulates Cell Cycle, Proliferation and Metastasis in Lung Adenocarcinoma via Targeting NEK2

OBJECTIVE: This study aimed to describe the mechanism of exosome-derived miR-486-5p underlying the cell cycle and progression in lung adenocarcinoma (LUAD). METHODS: Bioinformatics methods were applied for identifying the differentially expressed genes (DEGs) in the GEO-LUAD dataset, predicting wher...

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Detalles Bibliográficos
Autores principales: Hu, Huihui, Xu, Hangdi, Lu, Fen, Zhang, Jisong, Xu, Li, Xu, Shan, Jiang, Hanliang, Zeng, Qingxin, Chen, Enguo, He, Zhengfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156548/
https://www.ncbi.nlm.nih.gov/pubmed/32322578
http://dx.doi.org/10.3389/fbioe.2020.00259