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Kinesin-1 regulates antigen cross-presentation through the scission of tubulations from early endosomes in dendritic cells
Dendritic cells (DCs) constitute a specialized population of immune cells that present exogenous antigen (Ag) on major histocompatibility complex (MHC) class I molecules to initiate CD8 + T cell responses against pathogens and tumours. Although cross-presentation depends critically on the traffickin...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156633/ https://www.ncbi.nlm.nih.gov/pubmed/32286311 http://dx.doi.org/10.1038/s41467-020-15692-0 |