Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome

The differential production of transcript isoforms from gene loci is a key cellular mechanism. Yet, its impact in protein production remains an open question. Here, we describe ORQAS (ORF quantification pipeline for alternative splicing), a pipeline for the translation quantification of individual t...

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Detalles Bibliográficos
Autores principales: Reixachs-Solé, Marina, Ruiz-Orera, Jorge, Albà, M. Mar, Eyras, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156646/
https://www.ncbi.nlm.nih.gov/pubmed/32286305
http://dx.doi.org/10.1038/s41467-020-15634-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156646/
https://www.ncbi.nlm.nih.gov/pubmed/32286305
http://dx.doi.org/10.1038/s41467-020-15634-w

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