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Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome
The differential production of transcript isoforms from gene loci is a key cellular mechanism. Yet, its impact in protein production remains an open question. Here, we describe ORQAS (ORF quantification pipeline for alternative splicing), a pipeline for the translation quantification of individual t...
Autores principales: | Reixachs-Solé, Marina, Ruiz-Orera, Jorge, Albà, M. Mar, Eyras, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156646/ https://www.ncbi.nlm.nih.gov/pubmed/32286305 http://dx.doi.org/10.1038/s41467-020-15634-w |
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